JResponsive will organize your content in an efficient, dynamic and responsive layout. It can be applied to a container element and it will arrange its children in a layout that makes optimal use of screen space, by “packing” them in tightly. One of the very famous website that using this type of layout is Pulse.
A simple jQuery plugin that allows you to add a dynamically-resized layout to any page or element, customize the layout the way you want with or without top,right,left or bottom navigations.