This paper identifies five water environmental problems in the Delta that are the principal limiting factors of agricultural production and human health, i.e. (i) the salinity intrusion in the coastal areas, (ii) the effect of acid sulfate soils, (iii) the polluted water from human activities, (iv) the fresh water shortage in the dry season and (v) the flood in the rainy season. The discussion and conclusion present the people’s adaption strategies and water gorvernance issues in pursing sustainable management in the region.